By Gilbert N Ling
Unique 1963 assessment by means of Jay Jacobs, MD:
A actual concept of the residing nation: The Association-Induction speculation. by way of GILBERT Ning LING, B.Sc., PH.D., Director of the dep. of Molecular Biology, Pennsylvania Hospital.
Cloth, Pp. 680, with illustrations. Blaisdell Publishing Co.,A department of Random condominium. Inc., long island, London, 1962.
The writer has been famous in his box for 15 years. His paintings is praised through his friends, together with Dr. C. N. Yang, a Nobel Laureate in Physics. This e-book used to be written to coordinate actual chemistry, biochemistry and body structure, and clarify a number of the intricacies of dwelling tissue.
The contents are on such a complicated point that these acquainted with one element could be baflled through others. to assist in overcoming this trouble and to bridge the space among clinical disciplines there's a word list of seventy one pages.
Unfortunately, the mathematical calculations in a few parts are too complex for a person who has now not had really good training.
The diversity of topics is wide; habit of Ions, nonelectrolytes and proteins; mobile potentials and permeabillty; excitatton, contraction and inhibition; the activities or enzymes, hormones, and medication; development and neoplasm. The author's "association-induction" speculation is drawn upon to give an explanation for the phenomena or chemical motion in residing tissue. This speculation states that the associatlon among proteins and interacting debris is significantly various in vivo and In vitro, and that the first functionality of the polarizable resonating chain of a protein is to supply a motor vehicle for the transmission of an inductive effect.
The ebook comprises many tables, graphs, diagrams and mathematical calculations to help its theses. The bibliography and references are extensive.
Every health practitioner may still learn a few parts of this e-book, to work out how a ways the fundamental scientists have are available in figuring out the habit of residing tissue. it's of price mostly as a reference ebook to these whose paintings is on the easy technological know-how point.
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Additional resources for A Physical Theory of the Living State the association-induction hypothesis
1. 2. 3. Association Phenomena in Semiftxed-Charge Systems 17 A. Micellar aggregates 17 B. 4. Association of Counterions in True Fixed-Charge Systems 22 A. The effects of energy and entropy on dissociation phenomena 23 (I) The configurational entropy of dissociation in a fixed-charge system 25 (2) The rotational entropy of dissociation in a :fixed-charge system 27 (3) The effect of the adsorption energy on ionic association 29 B. Nonliving three-dimensional fixed-charge systems 29 (1) Exchange resins 29 (2) Ion-selectivity properties of other nonliving fixed-charge systems 32 C.
The applicability of the concept of ionic association to living protoplasm in general is shown in Chapter 3, where the density of fixed ionic sites in cellular and noncellular living matter is comprehensively examined. In short, Chapters 1 (received March 17, 1961), t 2, and 3 (received April 3, 1961) are primarily concerned with association phenomena and Chapters 4, 5, and 6 (received April 26, 1961) develop the major theme of association and induction. The wide applicability of these concepts is discussed first in Chapter 7 (received May 16, 1961), "The Theory of Proteins," which extensively develops the theme in relation to studies of isolated protein in vitro, and then in Chapters 8 to 18 (Chapter 8 received May 16, 1961; Chapters 9 and 10 received May 29, 1961; Chapters ll through 18 received July 10, 1961), which cover living protoplasm.
L Here nv is the number of molecules in the vapor state. 3 kcaljmole;t at room temperature exp (LlH/kT) is thus * There is no significant contribution to the entropy by vibrational degrees of freedom in water vapor (Rushbrooke, 1949). H represents the enthalpy change when both the reactant, water, and product, vapor, are in their respective standard states. F 0 , etc. 10 Association 5 X 10- 9, a figure so small that one wonders how sublimation may occur at all. Of course, sublimation does occur; thus, on a clear subzero wintry day, laundry dries in the open air.
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